The problem with Clays in .45 ACP is that you run out of pressure limits before you get to major caliber loads.
It works fine for light loads, and I have shot a good bit of it that way.
Traded into an 8 lb cannister and MAN that goes a LONG way in pistols.
Hodgdon max is 888fps with a LSWC 200 gr, the old Major Caliber was 900 fps, so we shot 925 to
be sure. Current wimpified major is, IIRC, down to 165K, so this actually makes it safely.
For 230 cast, max is just under 800 fps, again, short of the normal 230 velocity of 825-840 fps.
Still reasonable loads, but Clays is a touch too fast and pressure spikey for .45 ACP.
Bill