I have just one 45 Colt these days, but it is a jewel--my Ruger Bisley Blackhawk x 7.5". I did have to finish building it--the cylinder throats were .448"-.449" out of the box paired with a .452" groove diameter. I opened the throats to ,453" and size slugs to ,454" and it shoots VERY WELL. In recent years Ruger has begun producing revolvers in completed form, though the 90%-finished variants had a charm all their own.
I have room for another 45 Colt revolver, likely with 4"-5" barrel length. I've had a couple Uberti Cattleman x 4.75", and those are light, handy field arms. One of the Colt Anacondas would be just fine as well, if the 4.25" barrels go into production in 45 Colt. They aren't as light to carry, but everything is a trade-off.