Chargar summed up the matter succinctly above.
I have never been a huge user of wadcutter-form bullets, and similar things can be said for old-school RN forms as well. My mentors and I were steeped deeply in the semi-wadcutter/Keith-pattern cult, and despite several attempts at de-programming and other therapies I remain an acolyte of St. Elmer.
The tallest barrier to revolver accuracy for me has always been ME. Humans were not designed to be efficient artillery carriages, and my own shortcomings bear this out succinctly. On the core subject of this thread--I have never fired target-grade 38 Special RN loads. I have run a few thousand match wadcutter factory loads through known accurate 38 revolvers, and nothing I reload can best their accuracy. I get close with swaged HBWCs, but not quite. Cast WCs (Lymans #313492 and #358432) can't quite best handloaded HCWCs. SWCs run very close to to my cast WCs--which illustrate that the loosest element here is the steering wheel, not the drive train. ME AGAIN.
Very little of this shooting has been at 50 yards--most of my handgun target testing happens at 25 yards. The small bit of 50 yard handgunning has been done mostly with my most accurate handgun--my S&W Model 16-4 x 6". HBWC handloads (Hornady swaged bullets) shoot slightly better than both Lyman #313492 and the RCBS #32-98-SWC, which are a dead heat at 50. The castings do that at more than half-again the velocity of the HBWCs, though. I have cartwheeled a ground squirrel at 115 yards offhand with the RCBS bullet run at 1100 FPS. Sender and recipient were both surprised.