Gary, have you verified that your rounds fit the chamber? I am using an Accurate 46-305S mold cut to drop at .457” and after coating sized to .4585”, any larger and failure to chamber fully occurs. See the thread I did about this here: https://www.artfulbullet.com/index.php?threads/accurate-46-305s-for-458-socom-msr.6991/
Since that time I have also done some load work up with Shooters World Heavy Pistol that shows promise.