I could still be wrong but have been saying you have a lockup problem on one or more holes since you first started showing pictures of the smeared bullets. This problem may get worse 'under fire', but your checkamathingy showed that you probably have at least some static misalignment and I feel that's a lot of your problem.
I also think your bullets need more relief in the lube and crimp grooves, like the drawing I posted a few pages back. I got the bullets and gas checks you sent, will attempt to get some loads fired and bullets recovered this weekend.
Ruger gang-bores and gang-reams their revolver cylinders. They do not sharpen or replace all their reamers at once, only on an as-needed basis, one at a time. So you can have a sharp, new reamer right next to a worn or chipped one, and even the new ones may not be ground all exactly the same. The result is some holes elliptical, some undersized, some on size, some clean, some very rough.....and if there's a bad flute on the boring head, a whole chamber can walk.