Given the small particle size and high percentage of deterrent coating in proportion to the base grain, 296 and similar H110 would not lend themselves to tolerating free airspace in the case. I would expect poor ballistic uniformity and erratic ignition.
Fast-burning pistol powders which do not have a heavy deterrent coating, such as TiteGroup, 231, WST, 452AA perform well in light small game and gallery loads below 1300 fps. I find that 8.5 grains of WST in the .30-'06 with the Accurate 31-160H very accurate and the mild load does not require using a GC. It shoots to point of aim at 100 yards using 500-yard sight dope for military 152-grain Ball M2 in the 03A3 Springfield.