This can easily migrate into the to cock and lock or not .
I believe that once a person has sufficient skills and any measure of recurring training ........ Its own bucket of snakes also . That the easiest best solution will always be anything that functions like a computer mouse , point and click . Particulars of the circumstances tend to dictate the tool of choice , a loaded , safe off shotgun is waiting for an accident , I read a dozen stories one year about dogs shooting owners in duck blinds .
If it'll stop or break up in 1-1/2" of sheet rock a medium jacket of denim and a leather vest are going to prevent life threatening leaks .
I'm told that within 30' , circa 2003 anyway , that a RN 22LR was an imminent threat to a typical 9/357 compatible bullet vest . The same Deputy told me the next most terrifying tool was a bow with a old Grizzly or Zwicky Eskimo type single plane broad head . No LE training although I was an armed guard for a brief stent .
With the above and the bulk of my life being more likely to have a range cow , lion , or bear in my living room than a 2 legged sort I stand by a DAO , DA , or a grip/trigger type safety like a XD or 1911 (as practical examples not necessarily preferred types) .
If you have to think about it in time of need you ;
Have too many variations .
Too complex a tool .
Not enough time in .
You don't have to Jerry Mikilick (sp) , odds are in your favor that the other guy is no Wyatt Earp either .