I have a 2-1/2" speed six in 38 special that is a favorite. It balances well and just feels right in the hand.
I used to have the same thing in 9mm, but the cylinder would bind so I sent it in to Ruger for repair. They said they couldn't fix it, but offered me a very generous credit towards any new firearm, if I decided to leave it with them. So I bit the hook they offered, and came away with a 4" Redhawk in 45 LC.
I started collecting Six series handguns in 38 special roll marked with the 200th year Bi-Centennial. I have fond memories of the Bi-Centennial celebration and patriotism shared by most all back then. My Speed Six isn't a Bi-Centennial, but I sort of got carried away with the 38 special only chambering theme.
The opening thread talking of the NOS in the box reminded me of my foolish decision. My buddy and I stopped at our favorite pawn shop a couple of years ago. They had a 2-1/2" blued Security Six with the original box that looked as though it had never been fired. They wanted $475, which wasn't unreasonable considering the condition. I gave it a week to think it over, and it was gone when we went back. I still regret not buying it.