You took one look at my targets and immediately said I needed to throw away my lube. I've been using that lube for 5 years, along with all of my friends...........who all swear by it. I had no idea it was a bad lube. No reason to think it was a bad lube.
I never intended to mean it was a bad lube in a general way, I said the powder you're using and the "system", meaning bullet, alloy, rifle, charge weights, etc. doesn't happen to like it in that instance, and your targets were telling you that. It worked a lot better with Unique in that rifle, didn't it? That should tell you something. Given the observation that the lube isn't flowing well, is picking up excess powder residue, not clearing itself out of the bore every shot but every few shots, think about why it isn't working with the 4198 at mid-teens in peak PSI. I mentioned it is too viscous and too slippery for the low-pressure start and for the amount of trash the powder is leaving behind. So if you want to continue working with 4198, change the lube first and keep working with charge weights and seating depth (you might find 4198 will shoot better with the bullet snugged up into the throat). Or switch powders and keep using the same lube. Which powder to switch to? A faster-burning one that will peak pressure and heat faster and get that lube flowing. Seating the bullet longer to touch the throat will also bump pressure and bump the pressure curve up toward the ignition end, possibly accomplishing the same thing. Or, keep going UP in powder and leave all else the same, you have some headroom left to go with the 4198 to see if it will start to clean up and begin to develop a consistent bore condition and consistent ignition and burn curve at the same time. Lots of things to try.
Take a deep breath and consider what you've done so far. You've gotten your cartridge to fit the chamber better, reduced the tolerances there so the bullet has a better chance of physically hitting the ball seat in the middle. But your groups were drastically worse than what you were attempting to improve before....so look at what else you changed. You changed powder and seating depth. How could changing those things in the particular way you changed them be a step backwards? It's a puzzle to ponder and work out some theoretical solutions, ask questions about them, and make some decisions about what to try next.