I'm a long time user of 4759. I have a good stash of it still and it's discontinuation, probably won't effect me but, I really hate loosing it for others to use.
It was the last of the SR (Sporting Rifle) powders and I believe the last of the uncoated slow pistol/rifle type powders. Because of the lack of coating, it was very easy to ignite.
I truely believe that it is being discontinued, souly because Hodgdon wants to increase profits at the expensive of cast bullet shooters!
Regarding it's replacement powder 5744, I've never used it and I will never use it. From what I know about it, it shoots dirty in most, if not all applications. I will have to concede that it can be accurate, as the 200 & 300 yard CBA, Milsurp records are held by it.
There is a very long thread over at the ASSRA Forum, that envolves 5744, if you have the time, it's well worth reading.
http://www.assra.com/cgi-bin/yabb/YaBB.pl?num=1434466391
Two different rifles (single shots) have blown up, using it and it's not clear if they double charged the cases, one admits to using a wad on the powder but, that usually only produces a "ring" in the chamber.
Frank